Assess risk of bleeding from anticoagulation in atrial fibrillation
The HAS-BLED score was derived from a cohort of 3978 in the Euro Heart Survey on AF. A bleeding risk score termed HAS-BLED is an acronym for Hypertension, Abnormal liver/renal function, Stroke history, Bleeding predisposition, Labile INR, Elderly, Drug/alcohol usage.
|Renal disease (dialysis, transplant, Cr >2.26 mg/dL or 200 µmol/L)||+1|
|Liver disease (cirrhosis or bilirubin >2x normal with AST/ALT/AP >3x normal)||+1|
|Prior major bleeding or predisposition to bleeding||+1|
|Labile INR (unstable/high INRs, time in therapeutic range < 60%)||+1|
|Elderly (age >65)||+1|
|Medication usage predisposing to bleeding (aspirin, clopidogrel, NSAIDs)||+1|
|Alcohol usage (≥ 8 drinks/week)||+1|
|Score||Risk||Rate of major bleeding at 90 days|
|1.||Pisters R, Lane DA, Nieuwlaat R, de Vos CB, Crijns HJ, Lip GY. A novel user-friendly score (HAS-BLED) to assess one-year risk of major bleeding in atrial fibrillation patients: The Euro Heart Survey. Chest. 2010 Mar 18. Abstract|
|2.||Lip GY, Frison L, Halperin JL, Lane DA. Comparative validation of a novel risk score for predicting bleeding risk in anticoagulated patients with atrial fibrillation: the HAS-BLED (Hypertension, Abnormal Renal/Liver Function, Stroke, Bleeding History or Predisposition, Labile INR, Elderly, Drugs/Alcohol Concomitantly) score. J Am Coll Cardiol. 2011 Jan 11;57(2):173-80. Abstract|
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