Modified Duke Criteria for Infective Endocarditis
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Assist diagnosis of infective endocarditis
Definition of terms in Modified Duke Criteria for the diagnosis of infective endocarditis
|*Excludes single positive cultures for coagulase-negative staphylococci and organisms that do not cause endocarditis|
|Definite infective endocarditis|
Clinical criteria, using specific definitions for these terms as listed in the table above
Possible infective endocarditis, at least
† Viridans streptococci, Streptococcus bovis, HACEK group, Stapylococcus aureus OR Community- acquired enterococci, in the absence of a primary focus
‡ At least 2 positive cultures of blood samples drawn >12 h apart, OR All of 3 or a majority of ≥4 separate cultures of blood (with first and last sample drawn at least 1h apart)
º TEE recommended as first test in 1) prosthetic valve endocarditis; or 2) those with at least “possible” endocarditis by clinical criteria; or 3) those with suspected complicated endocarditis, such as paravalvular abscess. TTE recommended as first test in all other patients.
|1.||Li SJ, Sexton DJ, Mick N, Nettles R, Fowler VG, Jr, Ryan T, et al. Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis. 2000;30:633–638. Full text|
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Developer: Sirikarn Napan, MD, FACC