VALIANT Heart Failure Risk Score

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Clinical Use

Predict future heart failure hospitalization in patients with stable acute myocardial infarction

More Info

VARIANT study assessed the risk of an initial hospitalization for heart failure in 11,040 patients with acute myocardial infarction, without a prior history of heart failure, who had no major non-fatal cardiovascular events or deaths within 45 days of randomization. An integer-based risk score was developed using the parameter estimates of the 8 strongest predictors.


VALIANT heart failure risk scoring
FactorAssign pointsIf patient
Age0is 50 or younger
4is 51–60 years
5is 61–70 years
9is 71–80 years
10is older than 80
Race0is Caucasian or Asian
6is African-American
4is any other race
Diabetes0does not have diabetes
5has diabetes
Prior MI0has not had a prior MI
5has had a prior MI
PVD0does not have PVD
5has PVD
LBBB0does not have new LBBB
5has new LBBB
Killip Class0is Killip Class 1 or 2
3is Killip Class 3 or 4
NYHA class at 45 days0is Class I
3is Class II
5is Class III
9is Class IV


The graph below demonstrates distribution of scores and heart failure hospitalization event rate in each score category.

VALIANT Heart Failure Risk Score

European Heart Journal, Volume 29, Issue 6, 1 March 2008 1

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1.Eldrin F. Lewis, Eric J. Velazquez, Scott D. Solomon, Anne S. Hellkamp, John J.V. McMurray, Jasmine Mathias, Jean-Lucien Rouleau, Aldo P. Maggioni, Karl Swedberg, Lars Kober, Harvey White, Anthony J. Dalby, Gary S. Francis, Faiez Zannad, Robert M. Califf, and Marc A. Pfeffer. Predictors of the first heart failure hospitalization in patients who are stable survivors of myocardial infarction complicated by pulmonary congestion and/or left ventricular dysfunction: a VALIANT study. Eur Heart J. 2008 Mar;29(6):748-56. Abstract


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Developer: Sirikarn Napan, MD, FACC