ATRIA Bleeding Risk Score

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Clinical Use

Estimate bleeding risk for patients on warfarin

More Info

The ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) study followed up 13,559 adults with nonvalvular, nontransient atrial fibrillation with 9,186 patients on warfarin.1 There are 6 variables used for the calculation of the score.


ATRIA Bleeding Risk Scoring
Variable Points
Anemia +3
Severe renal disease/dialysis +3
Age ≥ 75 +2
Stroke history +1
Prior severe hemorrhage +1
Hypertension +1


Risk of major bleeding based on the ATRIA score
Score Risk Major bleeding at one year
<4 Low <1%
4 Intermediate 2.6%
>4 High 5.8%


1. Fang MC, Go AS, Chang Y, et al. A New Risk Scheme to Predict Warfarin-Associated Hemorrhage: The ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Study. J Am Coll Cardiol. 2011;58(4):395-401. doi:10.1016/j.jacc.2011.03.031.  Full text


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Developer: Sirikarn Napan, MD, FACC