The Outpatient Bleeding Risk Index (OBRI)

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Clinical Use

Estimate risk of bleeding from anticoagulation in atrial fibrillation

More Info

The Outpatient Bleeding Risk Index (OBRI) was developed in a population of 556 patients with venous thromboembolism who were discharged on warfarin therapy. It assigns one point for each of four variables.

Major bleeding according to the Outpatient Bleeding Risk Index
Points Major bleeding at one year1

0: Low risk


1 or 2: Intermediate risk


3 or more: High risk



1. Aspinall SL, DeSanzo BE, Trilli LE, Good CB. Bleeding Risk Index in an anticoagulation clinic. Assessment by indication and implications for care. J Gen Intern Med. 2005;20(11):1008–1013. Full text


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Developer: Sirikarn Napan, MD, FACC