TIMI Risk Score for UA/NSTEMI

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Clinical Use

A simple prognostication tool that categorizes risk for pateints presenting with unstable angina (UA) or non-ST elevation MI (NSTEMI).

More Info

TIMI risk score for UA/NSTEMI derived from a test cohort of the Thrombolysis in Myocardial Infarction [TIMI] 11B trial [August 1996–March 1998] and the Efficacy and Safety of Subcutaneous Enoxaparin in Unstable Angina and Non-Q-Wave MI trial [ESSENCE; October 1994–May 1996]).

The score assigns a value of 1 when an independent prognostic factor is present and 0 when it is absent.

Risk Factors
Age ≥65 years
≥3 CAD risk factors*
Known CAD with stenosis ≥50%
ASA use in last 7 days
Angina (≥2 episodes in the last 24 hrs)
EKG ST deviation ≥0.5 mm
Positive cardiac marker
*Risk factors for CAD: Family history of CAD, hypertension, hypercholesterolemia, diabetes, or current smoker


Summing the number of factors present categorizes patients into risk strata.

Score 0 or 1 point: Lower risk of adverse outcomes (death, MI, urgent revascularization)

Score 2 or more: Higher risk of adverse outcomes and may require more aggressive medical or coronary intervention.


1. Antman EM et al. The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making. JAMA. 2000 Aug 16;284(7):835-42. Full Text


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Developer: Sirikarn Napan, MD, FACC